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A few seconds later, presumably as the person responded to the humor, brain regions called the insula and amygdala became active across both hemispheres of the brain.
The areas most affected were the superior temporal, anterior insula , and orbitofrontal cortices.
The insular cortex is indented by a number of sulci, one of which - the central sulcus of the insula - is deeper and more prominent than the rest.
The insula relays messages between imitation and emotion regions, Iacoboni suggests.
While rejecting an offer, increased brain activity was observed in the anterior insula , which is associated with negative emotions such as disgust.
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