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Also, only the liver, pancreas, kidney, and intestine exhibit full activity of the trans-sulfuration pathway that metabolizes homocysteine to cysteine and taurine .
The downstream methionine metabolite taurine is necessary for amino acid and bile acid conjugation, and acylation reactions.
But the number of animals with the protective adaptation is dwindling, as local farmers give up their taurine herds for large zebu animals.
Janecek et al. found an anomalous association of yak with taurine cattle, which was explained by the sampling of an animal descending from a zebu via the maternal lineage.
Presumably, Hanotte said, trade also brought zebu bulls that farmers interbred with domesticated taurine cows, producing the mixed herds of today.
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